Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | F7 | P08709 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | F3 | P13726 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5075112 | 0.95 | PTGS1 (0.37) | PTGS1CYP2D6CYP2C19KDM4EALOX5 | |
| SCHEMBL5079078 | 0.90 | CYP2D6 (0.37) | PTGS1CYP2D6CYP2C19KDM4E | |
| SCHEMBL1698056 | 0.88 | CYP2D6 (0.36) | CYP2D6CYP2C19 | |
| SCHEMBL2873491 | 0.80 | CYP2D6 (0.39) | PTGS1CYP2D6CYP2C19KDM4E | |
| SCHEMBL5837166 | 0.78 | CYP2D6 (0.33) | CYP2D6CYP2C19ALOX5EPHX2SLC22A6 | |
| SCHEMBL5347005 | 0.76 | CYP2D6 (0.38) | CYP2D6CYP2C19 | |
| SCHEMBL5837042 | 0.76 | TSHR (0.33) | CYP2D6CYP2C19ALOX5EPHX2 | |
| SCHEMBL1698126 | 0.75 | CYP2D6 (0.36) | CYP2D6CYP2C19 | |
| SCHEMBL1698125 | 0.75 | CYP2D6 (0.36) | CYP2D6CYP2C19 | |
| SCHEMBL4257617 | 0.75 | CYP2D6 (0.36) | CYP2D6CYP2C19KDM4EEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1293521-B1 | Cyclic olefin addition copolymer and process for producing same, crosslinkable composition, crosslinked product and process for producing same, and optically transparent material and application thereof | JSR CORP (JP) | 2008-02-13 | — | — | EP | disclosed |
| US-6992154-B2 | Cyclic olefin addition copolymer and process for producing same, crosslinking composition, crosslinked product and process for producing same, and optically transparent material and application thereof | JSR CORPORATION (JP) | 2006-01-31 | — | — | US | disclosed |
| US-20050107552-A1 | Cyclic olefin addition copolymer and process for producing same, crosslinking composition, crosslinked product and process for producing same, and optically transparent material and application thereof | JSR CORPORATION (JP) | 2005-05-19 | — | — | US | disclosed |
| US-6844403-B2 | CYCLIC OLEFIN ADDITION COPOLYMER AND PROCESS FOR PRODUCING SAME, CROSSLINKING COMPOSITION, CROSSLINKED PRODUCT AND PROCESS FOR PRODUCING SAME, AND OPTICALLY TRANSPARENT MATERIAL AND APPLICATION THEREOF | JSR CORPORATION (JP) | 2005-01-18 | — | — | US | disclosed |
| US-20030119961-A1 | Cyclic olefin addition copolymer and process for producing same, crosslinking composition, crosslinked product and process for producing same, and optically transparent material and application thereof | JSR CORPORATION (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-1293521-A2 | Cyclic olefin addition copolymer and process for producing same, crosslinking composition, crosslinked product and process for producing same, and optically transparent material and application thereof | JSR Corporation (JP) | 2003-03-19 | — | — | EP | disclosed |