Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5073128 | 0.81 | AKT1 (0.54) | MAPK1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL5073130 | 0.81 | AKT1 (0.54) | MAPK1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL5858423 | 0.73 | MAPK1 (0.48) | MAPK1KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL5858418 | 0.73 | MAPK1 (0.48) | MAPK1KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL5855427 | 0.72 | MAPK1 (0.47) | MAPK1KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL5855413 | 0.72 | MAPK1 (0.47) | MAPK1KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL5856073 | 0.72 | MAPK1 (0.45) | MAPK1KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL621763 | 0.69 | ALDH1A1 (0.52) | MAPK1KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL16097184 | 0.69 | MAPK1 (0.51) | MAPK1KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL14338622 | 0.68 | ALDH1A1 (0.46) | MAPK1KMT2AMEN1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984385-A1 | METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN ORGANIC COMPOUNDS | MONASH UNIVERSITY (AU) | 2008-10-29 | — | — | EP | disclosed |
| EP-1984386-A1 | METHODS FOR THE SYNTHESIS OF TWO OR MORE DICARBA BRIDGES IN ORGANIC COMPOUNDS | Monash University (AU) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007093014-A1 | METHODS FOR THE SYNTHESIS OF TWO OR MORE DICARBA BRIDGES IN ORGANIC COMPOUNDS | MONASH UNIVERSITY (AU) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007093013-A1 | METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN ORGANIC COMPOUNDS | MONASH UNIVERSITY (AU) | 2007-08-23 | — | — | WO | disclosed |