Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.65 |
| ▸ | FTO | Q9C0B1 | 7/20 | 0.65 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.65 |
| ▸ | KDM6B | O15054 | 2/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29390250 | 0.79 | EGLN1 (1.00) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL522744 | 0.79 | EGLN1 (1.00) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL522656 | 0.75 | EGLN1 (0.71) | EGLN1FTOBBOX1KDM6BKDM5B | |
| SCHEMBL523005 | 0.73 | EGLN1 (0.67) | EGLN1FTOBBOX1KDM6BKDM5B | |
| SCHEMBL523385 | 0.72 | EGLN1 (0.70) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL5070927 | 0.72 | EGLN1 (0.49) | EGLN1FTOBBOX1KDM6BKDM5B | |
| SCHEMBL522971 | 0.72 | EGLN1 (0.80) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL522443 | 0.71 | EGLN1 (0.64) | EGLN1FTOBBOX1KDM6BTHRA | |
| SCHEMBL522699 | 0.70 | EGLN1 (0.74) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL523235 | 0.70 | EGLN1 (0.70) | EGLN1FTOBBOX1KDM6BKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893186-A2 | IMPROVED TREATMENT FOR ANEMIA USING A HIF-ALPHA STABILISING AGENT | FIBROGEN, INC. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006133391-A2 | IMPROVED TREATMENT FOR ANEMIA USING A HIF-ALPHA STABILISING AGENT | FIBROGEN, INC. (US) | 2006-12-14 | — | — | WO | disclosed |