Formaldehyde

Formaldehyde

SCHEMBL5073239

C=O.CC(C)c1cccc(OO)c1C(C)C.[NaH]

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRB2 P47870 2/20 0.41
LMNA P02545 2/20 0.41
FAAH O00519 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
GABRB1 P18505 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2C P28335 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
HTR2B P41595 1/20 0.41
GABRA2 P47869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35520 0.93 GABRA1 (0.46) GABRA1GABRG2GABRB3GABRB2LMNA
SCHEMBL29351216 0.93 GABRA1 (0.46) GABRA1GABRG2GABRB3GABRB2LMNA
Formaldehyde SCHEMBL5518379 0.90 GABRA1 (0.36) GABRA1GABRG2GABRB3GABRB2LMNA
SCHEMBL10395577 0.81 KMT2A (0.44) GABRA1LMNATSHRGABRB1LPAR1
SCHEMBL5705088 0.80 HPGD (0.38) GABRA1GABRG2GABRB3GABRB2LMNA
SCHEMBL9419446 0.80 LPAR1 (0.35) GABRA1GABRG2GABRB3GABRB2LMNA
SCHEMBL11299999 0.78 GABRA1 (0.43) GABRA1GABRG2GABRB3GABRB2LMNA
SCHEMBL11016029 0.78 MEN1 (0.35) GABRA1GABRG2GABRB3GABRB2LMNA
SCHEMBL9337114 0.77 GABRA1 (0.41) GABRA1GABRG2GABRB3GABRB2LMNA
SCHEMBL10768540 0.77 GABRA1 (0.34) GABRA1GABRG2GABRB3GABRB2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2599602-A1 Process for the treatment of woody essences C.S.M. S.a.s. (IT) 2013-06-05 EP claimed
EP-1207172-B1 Impact modifier combination for polymers ARKEMA INC (US) 2013-12-25 EP disclosed
EP-2599602-A1 Process for the treatment of woody essences C.S.M. S.a.s. (IT) 2013-06-05 EP disclosed
EP-1888685-A4 ACRYLIC COPOLYMERS WITH IMPROVED LOW TEMPERATURE PERFORMANCE ARKEMA INC (US) 2008-08-06 EP disclosed
EP-1888685-A2 ACRYLIC COPOLYMERS WITH IMPROVED LOW TEMPERATURE PERFORMANCE Arkema Inc. (US) 2008-02-20 EP disclosed
US-7314893-B2 Acrylic copolymers with improved low temperature performance ARKEMA INC. (US) 2008-01-01 US disclosed
WO-2006132796-A2 ACRYLIC COPOLYMERS WITH IMPROVED LOW TEMPERATURE PERFORMANCE ARKEMA INC. (US) 2006-12-14 WO disclosed
US-20060276587-A1 Acrylic copolymers with improved low temperature performance ARKEMA INC. 2006-12-07 US disclosed
US-7015282-B1 Impact additive of the core/shell type for thermoplastic polymers ARKEMA INC. (US) 2006-03-21 US disclosed
US-7015261-B1 Impact modifier combination for polymers ARKEMA INC. (US) 2006-03-21 US disclosed
US-RE37851-E1 ACRYLATED ESTER ATOFINA (FR) 2002-09-17 US disclosed
EP-1207172-A2 Impact modifier combination for polymers Atofina Chemicals, Inc. (US) 2002-05-22 EP disclosed
US-5773520-A Impact additive of the core/shell type for thermoplastic polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-06-30 US disclosed
US-4145380-A THREE-STAGE GRAFT POLYMER OF A VINYL AROMATIC COMPOUND AND CROSSLINKING AGENT; BUTADIENE, ISOPRENE, CHLOROPRENE OR AN ALKYL ACRYLATE; AND, AN ALKYL METHACRYLATE ROHM AND HAAS COMPANY (US) 1979-03-20 US disclosed
US-4064197-A THREE-STAGE GRAFT POLYMER ROHM AND HAAS COMPANY (US) 1977-12-20 US disclosed
US-3971835-A THREE-STAGE VINYLAROMATIC-ACRYLATE GRAFT POLYMER ROHM AND HAAS COMPANY (US) 1976-07-27 US disclosed