SCHEMBL5073280

SCHEMBL5073280

CCC(c1cccc2c1N(O)c1ccccc1S2)P(=O)(O)O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCHE P06276 12/20 0.40
MAPT P10636 3/20 0.40
NOX1 Q9Y5S8 1/20 0.39
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
CYP2C19 P33261 1/20 0.38
GAA P10253 1/20 0.37
POLB P06746 1/20 0.37
ATM Q13315 1/20 0.37
ACHE P22303 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
HTT P42858 1/20 0.36
GFER P55789 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4080952 0.82 BCHE (0.40) BCHEMAPTNOX1CYP2D6TSHR
SCHEMBL2496191 0.77 BCHE (0.38) BCHEMAPTNOX1CYP2D6TSHR
SCHEMBL4079882 0.75 PTGS1 (0.44) BCHEMAPTNOX1CYP2D6TSHR
SCHEMBL7620961 0.74 PTGS1 (0.43) BCHEMAPTNOX1CYP2D6TSHR
SCHEMBL5070736 0.74 BCHE (0.37) BCHEMAPTNOX1CYP2D6TSHR
SCHEMBL4343072 0.73 NOX1 (0.39) BCHENOX1POLBATMACHE
SCHEMBL4088074 0.71 BCHE (0.38) BCHEMAPTNOX1ACHE
SCHEMBL7617079 0.70 BCHE (0.42) BCHEMAPTNOX1HTT
SCHEMBL5073282 0.70 BCHE (0.47) BCHEMAPTNOX1CYP2D6TSHR
Phosphoric Acid SCHEMBL6395405 0.68 MEN1 (0.48) BCHEMAPTNOX1CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7358358-B2 Electrochromic compound NTERA LIMITED (IE) 2008-04-15 US disclosed
US-20050128561-A1 Electrochromic compound UNIVERSITY COLLEGE DUBLIN, A CONSTITUENT COLLEGE OF THE NATIONAL UNIVERSITY OF IRELAND 2005-06-16 US disclosed