SCHEMBL5073282

SCHEMBL5073282

CCC(N1c2ccccc2Sc2ccccc21)P(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BCHE P06276 12/20 0.47
MAPT P10636 2/20 0.47
CYP2D6 P10635 1/20 0.44
TSHR P16473 1/20 0.44
CYP2C19 P33261 1/20 0.44
GAA P10253 1/20 0.44
POLB P06746 1/20 0.44
ATM Q13315 1/20 0.44
PTGS1 P23219 2/20 0.44
PTGS2 P35354 2/20 0.44
NOX1 Q9Y5S8 1/20 0.44
ACHE P22303 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
MAOA P21397 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5566452 0.78 PTGS1 (0.47) BCHEMAPTCYP2D6TSHRCYP2C19
SCHEMBL502506 0.73 BCHE (0.55) BCHEMAPTCYP2D6TSHRCYP2C19
SCHEMBL12386881 0.73 PTGS1 (0.51) BCHEMAPTCYP2D6TSHRCYP2C19
SCHEMBL6276192 0.72 BCHE (0.47) BCHEMAPTCYP2D6TSHRCYP2C19
SCHEMBL5566417 0.72 BCHE (0.44) BCHEMAPTCYP2D6TSHRCYP2C19
SCHEMBL4595129 0.71 MAOA (0.48) BCHEMAPTCYP2D6TSHRCYP2C19
SCHEMBL5073280 0.70 BCHE (0.40) BCHEMAPTCYP2D6TSHRCYP2C19
SCHEMBL2862994 0.69 MEN1 (0.58) MAPTCYP2D6TSHRCYP2C19POLB
SCHEMBL29947127 0.69 MEN1 (0.58) MAPTCYP2D6TSHRCYP2C19POLB
SCHEMBL13485697 0.69 CYP2D6 (0.53) BCHEMAPTCYP2D6TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7358358-B2 Electrochromic compound NTERA LIMITED (IE) 2008-04-15 US disclosed
US-20050128561-A1 Electrochromic compound UNIVERSITY COLLEGE DUBLIN, A CONSTITUENT COLLEGE OF THE NATIONAL UNIVERSITY OF IRELAND 2005-06-16 US disclosed