SCHEMBL50733

SCHEMBL50733

CN1CC2CCC(C1)N2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14876645 1.00
SCHEMBL17188945 1.00
SCHEMBL21730404 1.00
Hydrochloric Acid SCHEMBL271156 0.97 CHRNB2 (0.39)
Hydrochloric Acid SCHEMBL29920122 0.97 CHRNB2 (0.39)
Hydrochloric Acid SCHEMBL611862 0.97 CHRNB2 (0.39)
SCHEMBL705004 0.88 CHRNB2 (0.35)
SCHEMBL24240867 0.84
SCHEMBL3936594 0.84
SCHEMBL16242450 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011526618-A 2011-10-13 JP claimed
US-20110166136-A1 Calcium Ion Channel Modulators &amp; Uses Thereof LECTUS THERAPEUTICS LIMITED (GB) 2011-07-07 US claimed
EP-2303840-A2 CALCIUM ION CHANNEL MODULATORS&amp;USES THEREOF Lectus Therapeutics Limited (GB) 2011-04-06 EP claimed
WO-2010001179-A2 CALCIUM ION CHANNEL MODULATORS &amp; USES THEREOF LECTUS THERAPEUTICS LIMITED (GB) 2010-01-07 WO claimed
US-12503473-B2 Triazolopyrimidine compounds and their use in treating cancer DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2025-12-23 US disclosed
US-20250382291-A1 SUBSTITUTED PYRROLO[2,3-b]PYRIDINES FOR SUPPRESSING TOXIC ENDOPLASMIC RETICULUM STRESS UNIV COLUMBIA (US) 2025-12-18 US disclosed
US-12331026-B2 Sulfonamido derivatives as cyclin-dependent kinase 2 inhibitors NIKANG THERAPEUTICS, INC. (US) 2025-06-17 US disclosed
US-12281060-B2 Remodilins for airway remodeling and organ fibrosis THE UNIVERSITY OF CHICAGO (US) 2025-04-22 US disclosed
US-12227500-B2 Substituted pyrrolo[2,3-b]pyridines for suppressing toxic endoplasmic reticulum stress THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-02-18 US disclosed
US-20240415851-A1 REMODILINS TO PREVENT OR TREAT CANCER METASTASIS, GLAUCOMA, AND HYPOXIA THE UNIVERSITY OF CHICAGO (US) 2024-12-19 US disclosed
US-20240383915-A1 OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER GENENTECH, INC. (US) 2024-11-21 US disclosed
CN-118955502-A Compounds with kinase inhibitory activity 上海赛岚生物科技有限公司 2024-11-15 CN disclosed
US-7271165-B2 Rifamycin analogs and uses thereof ACTIVBIOTICS, INC. (US) 2007-09-18 US disclosed
US-20070155715-A1 Rifamycin analogs and uses thereof ACTIVBIOTICS, INC. (US) 2007-07-05 US disclosed
US-20070142392-A1 Uses of rifamycins ACTIVBIOTICS, INC. (US) 2007-06-21 US disclosed
EP-1742944-A1 INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF Memory Pharmaceuticals Corporation (US) 2007-01-17 EP disclosed
WO-2006001894-A1 INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF MEMORY PHARMACEUTICAL CORPORATION (US) 2006-01-05 WO disclosed
US-20050250808-A1 Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof MEMORY PHARMACEUTICAL CORPORATION 2005-11-10 US disclosed
US-3951980-A 3-Substituted-8-methyl-3,8-diazabicyclo[3.2.1]octanes STANFORD RESEARCH INSTITUTE (US) 1976-04-20 US disclosed
US-3947445-A Diazabicyclooctanes and diazabicycloheptanes STANFORD RESEARCH INSTITUTE (US) 1976-03-30 US disclosed