Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5071388 | 0.86 | DRD2 (0.41) | MCHR1SLC6A4KCNH2LMNAMEN1 | |
| SCHEMBL641135 | 0.81 | MAPT (0.42) | SLC6A2SLC6A4SLC6A3LMNAMAPT | |
| SCHEMBL5073514 | 0.81 | CHRM1 (0.46) | MCHR1LMNAMAPTSIGMAR1MEN1 | |
| SCHEMBL642098 | 0.80 | NPSR1 (0.52) | SLC6A2SLC6A4SLC6A3LMNAMAPT | |
| SCHEMBL641134 | 0.78 | CNR1 (0.49) | LMNAMEN1KMT2ACHRM1ACHE | |
| SCHEMBL9965376 | 0.77 | SMN1; SMN2 (0.50) | SLC6A2SLC6A4SLC6A3LMNAMAPT | |
| SCHEMBL9965435 | 0.77 | CNR1 (0.49) | LMNAMAPTMEN1KMT2ACHRM1 | |
| SCHEMBL640909 | 0.77 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3LMNAMAPT | |
| SCHEMBL9965413 | 0.77 | CNR1 (0.46) | LMNAMAPTMEN1KMT2ACHRM1 | |
| SCHEMBL9965470 | 0.76 | NPSR1 (0.49) | LMNAMAPTMEN1KMT2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960347-A2 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | Sterix Limited (GB) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |