SCHEMBL5074029

SCHEMBL5074029

Cc1cccc2[nH]c(-c3ccccc3)nc12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 12/20 0.76
GAA P10253 12/20 0.76
SI P14410 12/20 0.76
MGAM2 Q2M2H8 12/20 0.76
HPSE Q9Y251 2/20 0.62
ESR1 P03372 1/20 0.62
RPS6KA3 P51812 1/20 0.62
TNKS O95271 1/20 0.62
PARP1 P09874 1/20 0.62
TNKS2 Q9H2K2 1/20 0.62
CBFB Q13951 1/20 0.62
KDM4E B2RXH2 1/20 0.61
NPC1 O15118 1/20 0.61
ALDH1A1 P00352 1/20 0.61
TP53 P04637 1/20 0.61
HPGD P15428 1/20 0.61
RAB9A P51151 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
HSD17B10 Q99714 1/20 0.61
ADORA3 P0DMS8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30615069 1.00 MGAM (0.76) MGAMGAASIMGAM2HPSE
SCHEMBL6056826 0.88 MGAM (0.77) MGAMGAASIMGAM2HPSE
SCHEMBL1170892 0.87 MGAM (0.71) MGAMGAASIMGAM2ESR1
SCHEMBL5201203 0.86 MGAM (1.00) MGAMGAASIMGAM2HPSE
SCHEMBL6325053 0.85 GAA (0.72) MGAMGAASIMGAM2HPSE
SCHEMBL13133302 0.85 MGAM (1.00) MGAMGAASIMGAM2HPSE
SCHEMBL2124325 0.85 MGAM (0.69) MGAMGAASIMGAM2HPSE
SCHEMBL1128986 0.85 MGAM (0.72) MGAMGAASIMGAM2HPSE
SCHEMBL10695650 0.85 MGAM (1.00) MGAMGAASIMGAM2HPSE
SCHEMBL30424685 0.84 MGAM (0.62) MGAMGAASIMGAM2HPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62180357-A None JP disclosed
CN-118047723-A Process for preparing benzoazacyclic compounds 常州大学 2024-05-17 CN disclosed
CN-116924995-A Method for synthesizing benzimidazole compound by catalyzing L-phenylalanine 宁夏师范学院 2023-10-24 CN disclosed
CN-115963697-A Radiation-sensitive composition, cured film, method for producing cured film, and display device JSR株式会社 2023-04-14 CN disclosed
CN-115268214-A Radiation-sensitive composition, cured film and method for producing the same, semiconductor and display device JSR株式会社 2022-11-01 CN disclosed
CN-110759903-B Novel synthesis method of thiabendazole 南开大学 2022-10-28 CN disclosed
CN-113552769-A Radiation-sensitive composition, cured film and method for producing same, semiconductor element, display element, and polymer JSR株式会社 2021-10-26 CN disclosed
CN-108043442-B Carbon-supported ruthenium nano material, preparation method thereof and application of carbon-supported ruthenium nano material in catalyzing reaction of alcohol and aromatic diamine 苏州大学 2021-03-19 CN disclosed
US-9994470-B2 Method of removing recalcitrant organic pollutants GENERAL ELECTRIC COMPANY (US) 2018-06-12 US disclosed
CN-108043442-A Ruthenium nano material of carbon load and preparation method thereof and the application in catalytic alcohol and aromatic diamines reaction 苏州大学 2018-05-18 CN disclosed
EP-2683660-A1 METHOD OF REMOVING RECALCITRANT ORGANIC POLLUTANT General Electric Company (US) 2014-01-15 EP disclosed
US-20130334135-A1 METHOD OF REMOVING RECALCITRANT ORGANIC POLLUTANTS BL TECHNOLOGIES, INC. 2013-12-19 US disclosed
WO-2012119266-A1 METHOD OF REMOVING RECALCITRANT ORGANIC POLLUTANT GENERAL ELECTRIC COMPANY (US) 2012-09-13 WO disclosed
EP-1984968-A1 IONIC LIQUID ELECTROLYTE Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2008-10-29 EP disclosed
WO-2007093961-A1 IONIC LIQUID ELECTROLYTE ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2007-08-23 WO disclosed
US-20070191372-A1 Dna-targeted benzotriazine 1,4-dioxides and their use in cancer therapy AUCKLAND UNISERVICES LIMITED (NZ) 2007-08-16 US disclosed
WO-1997020798-A1 IMPROVED METAL-LIGAND COMPLEX CATALYZED PROCESSES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-06-12 WO disclosed
JP-S62180357-A PHOTOPOLYMERIZABLE COMPOSITION DAICEL CHEM IND LTD 1987-08-07 JP disclosed
EP-0158027-A2 Method for making copper-clad base material for conductive plates DIELEKTRA GmbH (DE) 1985-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070191372-A1 Dna-targeted benzotriazine 1,4-dioxides and their use in cancer therapy HIF1AN, HIF1A, HYOU1 MGAM 4587/4885GAA 1039/4885SI 3891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.