Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21616869 | 1.00 | TSHR (0.50) | TSHRFAAHTRPV1PPARATHRB | |
| SCHEMBL7860226 | 1.00 | TSHR (0.50) | TSHRFAAHTRPV1PPARATHRB | |
| SCHEMBL322670 | 1.00 | TSHR (0.50) | TSHRFAAHTRPV1PPARATHRB | |
| SCHEMBL1678491 | 0.97 | TSHR (0.46) | TSHRFAAHTRPV1PPARA | |
| SCHEMBL1678870 | 0.90 | — | — | |
| SCHEMBL699652 | 0.78 | TSHR (0.48) | TSHRFAAHTRPV1PPARAEP300 | |
| SCHEMBL700497 | 0.78 | TSHR (0.48) | TSHRFAAHTRPV1PPARAEP300 | |
| SCHEMBL5200380 | 0.78 | PPARA (0.50) | TSHRFAAHTRPV1PPARA | |
| SCHEMBL8954181 | 0.78 | TSHR (0.48) | TSHRFAAHTRPV1PPARAEP300 | |
| SCHEMBL9012336 | 0.78 | TSHR (0.48) | TSHRFAAHTRPV1PPARAEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697465-B1 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GEN ELECTRIC (US) | 2008-02-13 | — | — | EP | disclosed |
| EP-1697465-A2 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061623-A2 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2005-07-07 | — | — | WO | disclosed |
| US-20050137310-A1 | Polymer nanocomposites and methods for their preparation | CITIBANK, N.A., AS COLLATERAL AGENT | 2005-06-23 | — | — | US | disclosed |