Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27809538 | 1.00 | TSHR (0.48) | TSHRPPARAEP300EPHX2FAAH | |
| SCHEMBL9012336 | 1.00 | TSHR (0.48) | TSHRPPARAEP300EPHX2FAAH | |
| SCHEMBL8954181 | 1.00 | TSHR (0.48) | TSHRPPARAEP300EPHX2FAAH | |
| SCHEMBL27526927 | 1.00 | TSHR (0.48) | TSHRPPARAEP300EPHX2FAAH | |
| SCHEMBL699652 | 1.00 | TSHR (0.48) | TSHRPPARAEP300EPHX2FAAH | |
| SCHEMBL27588305 | 1.00 | TSHR (0.48) | TSHRPPARAEP300EPHX2FAAH | |
| SCHEMBL266229 | 0.98 | TSHR (0.44) | TSHRPPARAEP300EPHX2FAAH | |
| SCHEMBL101407 | 0.90 | — | — | |
| SCHEMBL25090 | 0.79 | — | — | |
| SCHEMBL6630719 | 0.78 | GPR84 (0.33) | TSHRLMNAHSD17B10CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240156766-A1 | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | CYDEX PHARMACEUTICALS, INC. (US) | 2024-05-16 | — | — | US | disclosed |
| US-20240139137-A1 | Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | CYDEX PHARMACEUTICALS, INC. | 2024-05-02 | — | — | US | disclosed |
| EP-4274561-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | Quadriga Biosciences, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| US-20230348631-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | QUADRIGA BIOSCIENCES, INC. | 2023-11-02 | — | — | US | disclosed |
| CN-116847855-A | Pharmaceutical composition of chemotherapeutic agents based on beta-substituted beta-amino acid derivatives | 夸德里加生物科学公司 | 2023-10-03 | — | — | CN | disclosed |
| WO-2022148456-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | QUADRIGA BIOSCIENCES, INC. (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022147743-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | QUADRIGA BIOSCIENCES, INC. (US) | 2022-07-14 | — | — | WO | disclosed |
| US-20210379000-A1 | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2021-12-09 | — | — | US | disclosed |
| US-11020363-B2 | Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same | CYDEX PHARMACEUTICALS, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| US-10940128-B2 | Injectable melphalan compositions comprising a cyclodextrin derivative and methods of making and using the same | CYDEX PHARMACEUTICALS, INC. (US) | 2021-03-09 | — | — | US | disclosed |
| EP-0873342-A1 | 1,7-DIAROXY- OR 1,7-DIARYLTHIO-SUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND THEIR DIANHYDRIDES AND DIIMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| EP-0869959-A1 | 1,7-DISUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND DIANHYDRIDES AND DIIMIDES OF SAID ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997022608-A1 | 1,7-DISUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND DIANHYDRIDES AND DIIMIDES OF SAID ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-26 | — | — | WO | disclosed |
| WO-1997022607-A1 | 1,7-DIAROXY- OR 1,7-DIARYLTHIO-SUBSTITUTED PERYLENE-3,4,9,10-TETRACARBOXYLIC ACIDS AND THEIR DIANHYDRIDES AND DIIMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-26 | — | — | WO | disclosed |
| CN-1028961-C | Method for preparing medicinal solution | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-06-21 | — | — | CN | disclosed |
| CN-1020853-C | Pharmaceutical composition containing tricyclic compound or salt thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-05-26 | — | — | CN | disclosed |
| CN-1056103-A | Tricyclic compound, its production method and the pharmaceutical composition that contains this compound | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-11-13 | — | — | CN | disclosed |
| CN-1055110-A | Liquid medicine | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-10-09 | — | — | CN | disclosed |
| CN-1013687-B | Tricyclic compounds, process for their production and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-08-28 | — | — | CN | disclosed |
| CN-85109492-A | Tricyclic compounds, process for their production and pharmaceutical compositions containing them | — | 1986-06-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348631-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | BCAT1, BCAT2, DDC | TSHR 4801/4885PPARA 1397/4885EP300 4422/4885 |
| US-10940128-B2 | Injectable melphalan compositions comprising a cyclodextrin derivative and methods of making and using the same | MCL1, MYADM, IL2 | TSHR 3288/4885PPARA 3954/4885EP300 3626/4885 |
| US-11020363-B2 | Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same | GYS2, NOTUM, PYGL | TSHR 4211/4885PPARA 3759/4885EP300 4685/4885 |
| US-20210379000-A1 | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | MCL1, MYADM, IL2 | TSHR 3288/4885PPARA 3954/4885EP300 3626/4885 |
| US-20240156766-A1 | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | MCL1, MYADM, IL2 | TSHR 3288/4885PPARA 3954/4885EP300 3626/4885 |
| US-20240139137-A1 | Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | GYS2, NOTUM, PYGL | TSHR 4211/4885PPARA 3759/4885EP300 4685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.