⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354634 | 0.94 | — | — | |
| SCHEMBL11335821 | 0.80 | — | — | |
| SCHEMBL31484759 | 0.80 | — | — | |
| SCHEMBL27922799 | 0.76 | — | — | |
| SCHEMBL4350602 | 0.73 | — | — | |
| SCHEMBL27383258 | 0.72 | — | — | |
| SCHEMBL6048993 | 0.67 | — | — | |
| SCHEMBL433010 | 0.57 | — | — | |
| Lindane SCHEMBL8110265 | 0.51 | LMNA (1.00) | — | |
| SCHEMBL8406626 | 0.51 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8981126-B2 | Cyclopropenylidene-stabilized phosphenium cations | Studiengesellshaft Kohle mbH (DE) | 2015-03-17 | — | — | US | disclosed |
| US-20140288323-A1 | CYCLOPROPENIMINE CATALYST COMPOSITIONS AND PROCESSES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-09-25 | — | — | US | disclosed |
| US-20140051870-A1 | CYCLOPROPENYLIDENE-STABILIZED PHOSPHENIUM CATIONS | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2014-02-20 | — | — | US | disclosed |
| WO-2013059118-A1 | CYCLOPROPENIMINE CATALYST COMPOSITIONS AND PROCESSES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2013-04-25 | — | — | WO | disclosed |
| US-20080269525-A1 | SYNTHESIS OF STABLE CYCLOPROPENYLIDENES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-30 | — | — | US | disclosed |
| US-5622953-A | DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0691962-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022842-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |