Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | GPR183 | P32249 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5074689 | 1.00 | KMT2A (0.54) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL826798 | 0.93 | KMT2A (0.50) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL1194732 | 0.93 | KMT2A (0.50) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL826799 | 0.93 | KMT2A (0.50) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL1194436 | 0.91 | KMT2A (0.51) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL1194500 | 0.91 | KMT2A (0.51) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL1194433 | 0.91 | KMT2A (0.51) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL5973925 | 0.88 | PPARG (0.47) | KMT2APKMNFE2L2LMNAALDH1A1 | |
| SCHEMBL513626 | 0.88 | PPARG (0.47) | KMT2APKMNFE2L2LMNAALDH1A1 | |
| SCHEMBL513627 | 0.88 | PPARG (0.47) | KMT2APKMNFE2L2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370253-B1 | USE OF ALPHA, BETA UNSATURATED ARYL SULFONES FOR PROTECTING CELLS AND TISSUES FROM IONIZING RADIATION TOXICITY | UNIV TEMPLE (US) | 2008-09-03 | — | — | EP | disclosed |