Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | GPR183 | P32249 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826799 | 1.00 | KMT2A (0.50) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL1194732 | 1.00 | KMT2A (0.50) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL5074683 | 0.93 | KMT2A (0.54) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL5074689 | 0.93 | KMT2A (0.54) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL1194433 | 0.91 | KMT2A (0.51) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL1194500 | 0.91 | KMT2A (0.51) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL1194436 | 0.91 | KMT2A (0.51) | KMT2APKMNFE2L2GPR183MEN1 | |
| SCHEMBL5973925 | 0.88 | PPARG (0.47) | KMT2APKMNFE2L2FAAHPRSS1 | |
| SCHEMBL513626 | 0.88 | PPARG (0.47) | KMT2APKMNFE2L2FAAHPRSS1 | |
| SCHEMBL513627 | 0.88 | PPARG (0.47) | KMT2APKMNFE2L2FAAHPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896401-B1 | UNSATURATED SULFIDES, SULFONES, SULFOXIDES AND SULFONAMIDES SYNTHESIS | UNIV TEMPLE (US) | 2013-04-10 | — | — | EP | claimed |
| US-8143453-B2 | Unsaturated sulfides, sulfones, sulfoxides and sulfonamides synthesis | Temple University—Of the Commonwealth System of Higher Education (US) | 2012-03-27 | — | — | US | claimed |
| US-20090124828-A1 | Unsaturated Sulfides, Sulfones, Sulfoxides and Sulfonamides Synthesis | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-05-14 | — | — | US | claimed |
| EP-1896401-B1 | UNSATURATED SULFIDES, SULFONES, SULFOXIDES AND SULFONAMIDES SYNTHESIS | UNIV TEMPLE (US) | 2013-04-10 | — | — | EP | disclosed |
| US-8143453-B2 | Unsaturated sulfides, sulfones, sulfoxides and sulfonamides synthesis | Temple University—Of the Commonwealth System of Higher Education (US) | 2012-03-27 | — | — | US | disclosed |
| US-20090124828-A1 | Unsaturated Sulfides, Sulfones, Sulfoxides and Sulfonamides Synthesis | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124828-A1 | Unsaturated Sulfides, Sulfones, Sulfoxides and Sulfonamides Synthesis | SULT2A1, SULT1A1, ARSA | KMT2A 2578/4885PKM 3996/4885NFE2L2 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.