Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 20/20 | 0.72 |
| ▸ | ABCC8 | Q09428 | 20/20 | 0.72 |
| ▸ | KCNJ11 | Q14654 | 20/20 | 0.72 |
| ▸ | KCNJ8 | Q15842 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5075087 | 0.94 | ABCC9 (0.75) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6905789 | 0.89 | ABCC9 (0.72) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6904323 | 0.89 | ABCC9 (0.68) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6910304 | 0.85 | ABCC9 (0.67) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6908006 | 0.85 | ABCC9 (0.70) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL5074912 | 0.85 | ABCC9 (0.74) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7234724 | 0.84 | ABCC9 (0.55) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL5075094 | 0.84 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6431808 | 0.84 | ABCC9 (0.72) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6436245 | 0.84 | ABCC9 (0.72) | ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124828-B1 | PYRANO, PIPERIDINO, AND THIOPYRANO COMPOUNDS AND METHODS OF USE | ABBOTT LAB (US) | 2008-01-02 | — | — | EP | claimed |
| EP-1124828-A1 | PYRANO, PIPERIDINO, AND THIOPYRANO COMPOUNDS AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024743-A1 | PYRANO, PIPERIDINO, AND THIOPYRANO COMPOUNDS AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2000-05-04 | — | — | WO | disclosed |