Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102331 | 0.69 | PDPK1 (0.59) | PDPK1CYP2A6LOXL2HSP90AA1ADORA2A | |
| SCHEMBL2126189 | 0.69 | PDPK1 (0.45) | PDPK1CYP2A6LOXL2HSP90AA1ADORA2A | |
| SCHEMBL31556353 | 0.67 | PDPK1 (0.56) | PDPK1CYP2A6LOXL2HSP90AA1ADORA2A | |
| SCHEMBL30632310 | 0.67 | PDPK1 (0.56) | PDPK1CYP2A6LOXL2HSP90AA1ADORA2A | |
| SCHEMBL30534095 | 0.67 | PDPK1 (0.56) | PDPK1CYP2A6LOXL2HSP90AA1ADORA2A | |
| SCHEMBL1457635 | 0.64 | PDPK1 (0.39) | PDPK1CYP2A6LOXL2HSP90AA1ADORA2A | |
| SCHEMBL28884067 | 0.63 | SRC (0.35) | PDPK1CYP2A6LOXL2HSP90AA1ADORA2A | |
| SCHEMBL578376 | 0.63 | PDPK1 (0.52) | PDPK1CYP2A6LOXL2HSP90AA1ADORA2A | |
| SCHEMBL2935611 | 0.63 | PDPK1 (0.42) | PDPK1CYP2A6LOXL2HSP90AA1ADORA2A | |
| SCHEMBL2580491 | 0.63 | PDPK1 (0.38) | PDPK1CYP2A6LOXL2HSP90AA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934211-A1 | BIOCOMPATIBLE N, N-DISUBSTITUTED SULFONAMIDE-CONTAINING FLUORESCENT DYE LABELS | Visen Medical, Inc. (US) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007028037-A1 | BIOCOMPATIBLE N, N-DISUBSTITUTED SULFONAMIDE-CONTAINING FLUORESCENT DYE LABELS | VISEN MEDICAL, INC. (US) | 2007-03-08 | — | — | WO | disclosed |