Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75996 | 0.85 | TRPV1 (0.53) | F10TRPV1NAMPTKITMAPT | |
| SCHEMBL85889 | 0.78 | NAMPT (0.45) | F10TRPV1NAMPTEPHX2MAPT | |
| SCHEMBL4101126 | 0.77 | F10 (0.61) | F10MAPTCCR1 | |
| SCHEMBL75773 | 0.76 | F10 (0.63) | F10 | |
| SCHEMBL3834606 | 0.75 | F10 (0.62) | F10MAPT | |
| SCHEMBL3830301 | 0.74 | F10 (0.63) | F10MAPT | |
| SCHEMBL3832169 | 0.73 | F10 (0.62) | F10MAPTCCR1 | |
| SCHEMBL14286939 | 0.73 | F10 (0.76) | F10MAPT | |
| SCHEMBL14286920 | 0.73 | F10 (0.76) | F10MAPT | |
| SCHEMBL14286936 | 0.73 | F10 (0.76) | F10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080003214-A1 | Medicaments Comprising Carbonyl Compounds, And The Use Thereof | MERCK PATENT GMBH (DE) | 2008-01-03 | — | — | US | claimed |
| US-20080003214-A1 | Medicaments Comprising Carbonyl Compounds, And The Use Thereof | MERCK PATENT GMBH (DE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080003214-A1 | Medicaments Comprising Carbonyl Compounds, And The Use Thereof | F2, PDHX, SDHB | F10 22/4885TRPV1 2174/4885NAMPT 2823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.