SCHEMBL5075501

SCHEMBL5075501

CCC=CCCSOS(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 4/20 0.37
LPAR2 Q9HBW0 3/20 0.36
LPAR3 Q9UBY5 3/20 0.36
LPAR1 Q92633 1/20 0.36
ALDH1A1 P00352 6/20 0.33
CYP19A1 P11511 4/20 0.33
PPARG P37231 3/20 0.33
OXER1 Q8TDS5 3/20 0.33
MAPT P10636 3/20 0.33
RXRA P19793 2/20 0.33
FFAR1 O14842 2/20 0.33
GPR84 Q9NQS5 1/20 0.32
ADORA3 P0DMS8 2/20 0.32
NR1I2 O75469 2/20 0.32
PTGS2 P35354 2/20 0.32
PGR P06401 1/20 0.32
PDE4D Q08499 1/20 0.32
F7 P08709 3/20 0.32
F3 P13726 3/20 0.32
PPARA Q07869 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5078751 0.85 LPAR3 (0.41) LPAR2LPAR3LPAR1MAPTF7
SCHEMBL6298214 0.74
SCHEMBL10425429 0.71 TP53 (0.33) LPAR2LPAR3LPAR1
Dimethylamine SCHEMBL28075516 0.69
SCHEMBL5856225 0.69 CA2 (0.39) LPAR2LPAR3LPAR1MAPTPPARA
SCHEMBL1739737 0.69
SCHEMBL5138135 0.68 CA2 (0.42) LPAR2LPAR3LPAR1MAPTPPARA
SCHEMBL5136293 0.68 CA2 (0.42) LPAR2LPAR3LPAR1MAPTPPARA
SCHEMBL7715442 0.68 CA2 (0.42) LPAR2LPAR3LPAR1MAPTPPARA
SCHEMBL5136467 0.68 CA2 (0.42) LPAR2LPAR3LPAR1MAPTPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7417084-B2 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-08-26 US claimed
EP-1674292-A1 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-06-28 EP claimed
US-20060135660-A1 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY 2006-06-22 US claimed
US-7417084-B2 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-08-26 US disclosed
EP-1674292-A1 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-06-28 EP disclosed
US-20060135660-A1 Rubber compound containing an organothiosulfate and a bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY 2006-06-22 US disclosed
EP-0109955-B1 RUBBER/METAL COMPOSITES MONSANTO EUROPE S.A./N.V. (BE) 1988-01-20 EP disclosed
US-4704334-A ORGANIC THIOSULFATE ADHESION PROMOTERS MONSANTO EUROPE, S.A. (BE) 1987-11-03 US disclosed
US-4532080-A Cobalt or nickel salt of organic thiosulfate ester MONSANTO EUROPE, S.A. (BE) 1985-07-30 US disclosed
EP-0109955-A2 Rubber/metal composites MONSANTO EUROPE S.A./N.V. (BE) 1984-05-30 EP disclosed