SCHEMBL5075939

SCHEMBL5075939

C#CCOc1c(Cl)cc(OCc2ccccc2C(=NOCC)C(=O)O)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.40
HTT P42858 2/20 0.39
TP53 P04637 1/20 0.39
ALDH1A1 P00352 2/20 0.39
RAB9A P51151 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ABL1 P00519 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
RIN1 Q13671 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NR4A2 P43354 2/20 0.37
NPC1 O15118 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
MAOA P21397 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5079413 0.91 HTT (0.43) HIF1AHTTTP53ALDH1A1RAB9A
SCHEMBL6155058 0.91 HIF1A (0.49) HIF1AHTTTP53ALDH1A1RAB9A
SCHEMBL6155063 0.91 HIF1A (0.49) HIF1AHTTTP53ALDH1A1RAB9A
SCHEMBL5077140 0.87 HIF1A (0.51) HIF1AHTTTP53ALDH1A1RAB9A
SCHEMBL5079428 0.86 HIF1A (0.38) HIF1AHTTTP53ALDH1A1RAB9A
SCHEMBL5074686 0.83 HIF1A (0.39) HIF1AHTTTP53ALDH1A1RAB9A
SCHEMBL5080521 0.83 HIF1A (0.39) HIF1AHTTTP53ALDH1A1RAB9A
SCHEMBL5076407 0.83 HIF1A (0.39) HIF1AHTTTP53ALDH1A1RAB9A
SCHEMBL5079633 0.83 HIF1A (0.48) HIF1ATP53ALDH1A1RAB9AMEN1
SCHEMBL5079388 0.83 HIF1A (0.53) HIF1AHTTTP53ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT HIF1A 4554/4885HTT 4420/4885TP53 2842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.