Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155058 | 1.00 | HIF1A (0.49) | HIF1AHTTTP53ALDH1A1NR4A2 | |
| SCHEMBL5075935 | 0.91 | HIF1A (0.60) | HIF1AHTTTP53ALDH1A1NR4A2 | |
| SCHEMBL5075939 | 0.91 | HIF1A (0.40) | HIF1AHTTTP53ALDH1A1NR4A2 | |
| SCHEMBL6150401 | 0.91 | HIF1A (0.50) | HIF1AHTTTP53NR4A2NPC1 | |
| SCHEMBL6150397 | 0.91 | HIF1A (0.50) | HIF1AHTTTP53NR4A2NPC1 | |
| SCHEMBL5080505 | 0.89 | HIF1A (0.48) | HIF1AHTTTP53ALDH1A1NR4A2 | |
| SCHEMBL5080512 | 0.89 | HIF1A (0.48) | HIF1AHTTTP53ALDH1A1NR4A2 | |
| SCHEMBL5079388 | 0.88 | HIF1A (0.53) | HIF1AHTTTP53ALDH1A1NR4A2 | |
| SCHEMBL5079377 | 0.88 | HIF1A (0.53) | HIF1AHTTTP53ALDH1A1NR4A2 | |
| SCHEMBL5136664 | 0.87 | HIF1A (0.54) | HIF1AHTTTP53ALDH1A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494991-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | Isagro Ricerca S.r.l. (IT) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087032-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | ISAGRO RICERCA S.R.L. (IT) | 2003-10-23 | — | — | WO | disclosed |