Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5076107 | 1.00 | MAPT (0.42) | MAPTCYP2C19CYP2D6MEN1CYP3A4 | |
| SCHEMBL1194958 | 0.92 | AHR (0.38) | MAPTCYP2C19CYP2D6MEN1CYP3A4 | |
| SCHEMBL5871842 | 0.92 | MAPT (0.37) | MAPTCYP2C19CYP2D6MEN1CYP3A4 | |
| SCHEMBL7157126 | 0.92 | MAPT (0.40) | MAPTCYP2C19CYP2D6MEN1CYP3A4 | |
| SCHEMBL5872239 | 0.92 | MAPT (0.37) | MAPTCYP2C19CYP2D6MEN1CYP3A4 | |
| SCHEMBL1194574 | 0.92 | MAPT (0.40) | MAPTCYP2C19CYP2D6MEN1CYP3A4 | |
| SCHEMBL1194536 | 0.92 | AHR (0.38) | MAPTCYP2C19CYP2D6MEN1CYP3A4 | |
| SCHEMBL1194100 | 0.92 | MAPT (0.40) | MAPTCYP2C19CYP2D6MEN1CYP3A4 | |
| SCHEMBL1194770 | 0.92 | ALDH1A1 (0.41) | MAPTCYP2C19CYP2D6MEN1CYP3A4 | |
| SCHEMBL5074675 | 0.92 | AHR (0.38) | MAPTCYP2C19CYP2D6MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370253-B1 | USE OF ALPHA, BETA UNSATURATED ARYL SULFONES FOR PROTECTING CELLS AND TISSUES FROM IONIZING RADIATION TOXICITY | UNIV TEMPLE (US) | 2008-09-03 | — | — | EP | disclosed |