Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102009 | 0.91 | PRKCQ (0.37) | PRKCQPRKCD | |
| SCHEMBL5078819 | 0.84 | IRAK4 (0.37) | NR1I2CYP2E1EPHX2 | |
| SCHEMBL14647676 | 0.81 | PIM1 (0.39) | PRKCQNR1I2CYP2E1 | |
| SCHEMBL12518971 | 0.80 | NR1I2 (0.38) | NR1I2CYP2E1 | |
| SCHEMBL15015340 | 0.79 | RAB9A (0.42) | NR1I2CYP2E1 | |
| SCHEMBL15015289 | 0.78 | NR1I2 (0.34) | NR1I2CYP2E1 | |
| SCHEMBL173166 | 0.77 | PRKCQ (0.35) | PRKCQPRKCD | |
| SCHEMBL12518984 | 0.77 | NR1I2 (0.38) | NR1I2CYP2E1 | |
| SCHEMBL12949583 | 0.76 | IRAK4 (0.33) | NR1I2CYP2E1 | |
| SCHEMBL15015348 | 0.75 | NR1I2 (0.35) | NR1I2CYP2E1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080299080-A1 | Thiophene analogues for the treatment or prevention of flavivirus infections | VERTEX PHARMACEUTICALS (CANADA) INCORPORATED (CA) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299080-A1 | Thiophene analogues for the treatment or prevention of flavivirus infections | TTR, ZC3HAV1, IRF3 | PRKCQ 4722/4885PRKCD 4774/4885NR1I2 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.