Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051914 | 0.81 | MAPK14 (0.39) | MAPK14 | |
| SCHEMBL3061264 | 0.80 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL3051000 | 0.80 | MAPK14 (0.48) | MAPK14ALDH1A1 | |
| SCHEMBL3049670 | 0.78 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL3062020 | 0.77 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL3054278 | 0.77 | MAPK14 (0.59) | MAPK14ALDH1A1 | |
| SCHEMBL5138721 | 0.77 | MAPK14 (0.47) | MAPK14ALDH1A1 | |
| SCHEMBL3058462 | 0.76 | MAPK14 (0.44) | MAPK14ALDH1A1 | |
| SCHEMBL3054268 | 0.76 | ALDH1A1 (0.47) | MAPK14ALDH1A1LMNA | |
| SCHEMBL3051662 | 0.76 | MAPK14 (0.47) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907358-A2 | BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS | Palau Pharma, S.A. (ES) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007000340-A2 | BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS | PALAU PHARMA, S.A. (ES) | 2007-01-04 | — | — | WO | disclosed |