Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5076255 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EMAPTALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL1252189 | 0.99 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EMAPTALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL1252192 | 0.99 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL5082669 | 0.92 | ALDH1A1 (0.38) | SMN1; SMN2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL5082666 | 0.92 | ALDH1A1 (0.38) | SMN1; SMN2KDM4EALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1251911 | 0.91 | ALDH1A1 (0.38) | SMN1; SMN2KDM4EALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1251907 | 0.91 | ALDH1A1 (0.38) | SMN1; SMN2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL5079087 | 0.85 | HDAC3 (0.36) | SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5079091 | 0.85 | HDAC3 (0.36) | SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1253084 | 0.85 | HDAC3 (0.35) | SMN1; SMN2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608377-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARM INC (CA) | 2008-10-01 | — | — | EP | claimed |