Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5076277 | 1.00 | PDGFRB (0.38) | PDGFRBPDGFRAKDM4EALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL1254455 | 0.99 | PDGFRB (0.37) | PDGFRBPDGFRAKDM4EALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL1254454 | 0.99 | PDGFRB (0.37) | PDGFRBPDGFRAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1253333 | 0.89 | ALOX5 (0.36) | ALDH1A1 | |
| SCHEMBL1253332 | 0.89 | ALOX5 (0.36) | ALDH1A1 | |
| SCHEMBL1253275 | 0.86 | ALOX5 (0.37) | — | |
| SCHEMBL1253271 | 0.86 | ALOX5 (0.37) | — | |
| SCHEMBL726211 | 0.86 | HPGD (0.42) | — | |
| SCHEMBL726213 | 0.86 | HPGD (0.42) | — | |
| SCHEMBL5079829 | 0.85 | KDR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608377-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARM INC (CA) | 2008-10-01 | — | — | EP | claimed |