SCHEMBL5077484

SCHEMBL5077484

O=C1C=CC(=O)N1c1ccc(N2C(=O)C=CC2=O)c2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 4/20 0.68
MGLL Q99685 13/20 0.56
FAAH O00519 4/20 0.50
HSP90AA1 P07900 4/20 0.46
ALDH1A1 P00352 3/20 0.46
ATM Q13315 3/20 0.46
NPSR1 Q6W5P4 2/20 0.46
PKM P14618 1/20 0.46
CCR6 P51684 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HTT P42858 2/20 0.42
MITF O75030 1/20 0.42
HPGD P15428 1/20 0.41
XBP1 P17861 1/20 0.41
ALOX12 P18054 1/20 0.41
RUNX1 Q01196 1/20 0.41
CBFB Q13951 1/20 0.41
G6PD P11413 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31180023 1.00 TLR9 (0.68) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL3277562 0.90 TLR9 (0.68) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL31179969 0.90 TLR9 (0.68) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL28883423 0.88 MGLL (0.60) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL30634197 0.88 TLR9 (0.54) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL28883555 0.88 MGLL (0.60) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL2053114 0.88 TLR9 (0.54) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL5062133 0.88 ESR1 (0.55) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL28883506 0.88 MGLL (0.60) TLR9MGLLFAAHHSP90AA1ALDH1A1
SCHEMBL28883430 0.83 TLR9 (0.48) TLR9MGLLFAAHHSP90AA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300585-A Having improved cure reversion THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-04-05 US claimed
US-4935297-A BISMALEIMIDE MODIFIED RUBBERS, PHENOLIC RESINS AND AMINO RESINS BRIDGESTONE CORPORATION (JP) 1990-06-19 US claimed
EP-4039733-A1 METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN Arkema, Inc. (US) 2022-08-10 EP disclosed
EP-4013810-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT Sika Technology AG (CH) 2022-06-22 EP disclosed
US-20220112373-A1 THERMOSETTING RESIN COMPOSITION SHOWA DENKO K.K. (JP) 2022-04-14 US disclosed
CN-109689742-B Curable resin mixture and method for producing curable resin composition 昭和电工株式会社 2021-12-10 CN disclosed
EP-2970605-B1 METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN ARKEMA INC (US) 2021-12-01 EP disclosed
US-20210284783-A1 METHODS FOR PRODUCING CURABLE RESIN MIXTURE AND CURABLE RESIN COMPOSITION SHOWA DENKO K.K. (JP) 2021-09-16 US disclosed
CN-113316597-A Thermosetting resin composition 昭和电工株式会社 2021-08-27 CN disclosed
US-11078358-B2 Curable composition including epoxy resin and curable solid filler 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-08-03 US disclosed
WO-2021028599-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT SIKA TECHNOLOGY AG (CH) 2021-02-18 WO disclosed
EP-0345825-B1 RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-11 EP disclosed
US-5109055-A Blend with a dinitrodiamine compound with n-(cyclohexylthio)-phthalimide and(or) 2,3,5,6-tetrachloro-1,4-benzoqionone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-28 US disclosed
EP-0410152-A1 Rubber composition having excellent dynamic properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-30 EP disclosed
US-4960833-A Rubber composition with nitrogen and phosphorous compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-02 US disclosed
EP-0191931-B1 RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-07-04 EP disclosed
US-4935297-A BISMALEIMIDE MODIFIED RUBBERS, PHENOLIC RESINS AND AMINO RESINS BRIDGESTONE CORPORATION (JP) 1990-06-19 US disclosed
EP-0345825-A1 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-12-13 EP disclosed
US-4803250-A AROMATIC CARBOXYLIC ANHYDRIDE, BISMALEIMIDE, SULFUR, ACCELERATOR, NONREVERTING, ANTICRACKING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-02-07 US disclosed
EP-0191931-A2 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-27 EP disclosed