SCHEMBL5077536

SCHEMBL5077536

IC1C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13699453 0.60
SCHEMBL3929943 0.46
Krypton Kr 81M SCHEMBL30924272 0.38
Charcoal, Activated SCHEMBL8562816 0.38
SCHEMBL29889134 0.38
SCHEMBL98004 0.38
SCHEMBL6559802 0.38
SCHEMBL3381929 0.38
SCHEMBL5427530 0.38
Fluoride Ion SCHEMBL73611 0.27

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170066790-A1 Fluorescent Labeled Inhibitors CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-03-09 US disclosed
EP-2315763-B1 BENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS GLAXOSMITHKLINE LLC (US) 2016-06-01 EP disclosed
US-20120195913-A1 COMPOSITIONS AND METHODS OF USE FOR THERAPEUTIC ANTIBODIES NOVARTIS AG (CH) 2012-08-02 US disclosed
US-20120033639-A1 SYSTEM AND APPARATUS FOR CONVERGING WIMAX AND WIFI NETWORKS HUAWEI TECHNOLOGIES CO., LTD. (CN) 2012-02-09 US disclosed
EP-2404904-A1 5-lipoxygenase-activating protein (FLAP) inhibitors Amira Pharmaceuticals, Inc. (US) 2012-01-11 EP disclosed
US-20110112299-A1 TETRACYCLIC COMPOUND KYOWA HAKKO KIRIN CO., LTD. (JP) 2011-05-12 US disclosed
US-20100331325-A1 NOVEL SUBSTITUTED TETRACYCLIC TETRAHYDROFURAN, PYRROLIDINE AND TETRAHYDROTHIOPHENE DERIVATIVES CID-NUNEZ JOSE MARIA 2010-12-30 US disclosed
US-7834008-B2 neurokinin receptor 3 (NK3) antagonists; psychological disorders, inflammatory bowel disease, asthma, ischemia, Parkinson's disease; e.g. (1S,2R)-2-(4-Acetylamino-4-phenyl-piperidin-1-ylmethyl)-1-(3,4-dichlorophenyl)-cyclopropanecarboxylic acid, benzyl-methyl-amide H. LUNDBECK A/S (DK) 2010-11-16 US disclosed
US-7799785-B2 Substituted tetracyclic tetahydrofuran, pyrrolidine and tetrahydrothiophene derivatives JANSSEN PHARMACEUTICA NV (BE) 2010-09-21 US disclosed
US-7798613-B2 Pagewidth printhead assembly SILVERBROOK RESEARCH PTY LTD (AU) 2010-09-21 US disclosed
US-7544808-B2 Tricyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2009-06-09 US disclosed
US-7544236-B2 Phthalocyanine compounds and their use in ink-jet printing FUJIFILM IMAGING COLORANTS LIMITED (GB) 2009-06-09 US disclosed
US-20080287450-A1 Novel Substituted Tetracyclic Tetahydrofuran, Pyrrolidine And Tetrahydrothiophene Derivatives JANSSEN PHARMACEUTICA, NV (BE) 2008-11-20 US disclosed
US-20080269525-A1 SYNTHESIS OF STABLE CYCLOPROPENYLIDENES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-10-30 US disclosed
EP-1395176-B1 METHOD FOR MONITORING CONSCIOUSNESS COMPUMEDICS LTD (AU) 2008-10-15 EP disclosed
EP-1970379-A1 NON-PROTEOLYSABLE OLIGOPEPTIDES THAT INHIBIT GLYCOPROTEIN GP41 OF THE AIDS VIRUS Universidad del Pais Vasco (ES) 2008-09-17 EP disclosed
US-20080132706-A1 Compounds as PDE IV and TNF Inhibitors AVENTIS PHARMA LIMITED (GB) 2008-06-05 US disclosed
US-20080110369-A1 Phthalocyanine Compounds And Their Use In Ink-Jet Printing FUJIFILM IMAGING COLORANTS LIMITED (GB) 2008-05-15 US disclosed
US-20080108288-A1 Conductive Polishing Article for Electrochemical Mechanical Polishing APPLIED MATERIALS, INC. 2008-05-08 US disclosed
US-7360871-B2 Inkjet chamber with ejection actuator between inlet and nozzle SILVERBROOK RESEARCH PTY LTD (AU) 2008-04-22 US disclosed