SCHEMBL5077849

SCHEMBL5077849

CCC(OC(=O)CS)OC(=O)CS

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
LMNA P02545 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9420714 0.89 TSHR (0.46) TSHRHSD17B10
SCHEMBL9420707 0.87 TSHR (0.39) TSHRHSD17B10
SCHEMBL632803 0.81 TSHR (0.42) TSHRHSD17B10LMNA
SCHEMBL1362097 0.79 CYP2C19 (0.39) LMNA
SCHEMBL2145422 0.78
SCHEMBL6741077 0.78
SCHEMBL2815454 0.78 SMPD1 (0.41) TSHRHSD17B10LMNA
SCHEMBL2106060 0.78 SMPD1 (0.46) TSHRHSD17B10LMNA
SCHEMBL1050084 0.76 TSHR (0.43) TSHRHSD17B10
SCHEMBL1848801 0.75 TRPA1 (0.48) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2752684-B1 METHOD FOR PRODUCING POLYURETHANE LENS HOYA CORP (JP) 2017-07-12 EP claimed
US-20140296431-A1 METHOD FOR PRODUCING POLYURETHANE LENS HOYA CORPORATION (JP) 2014-10-02 US claimed
EP-2752684-A1 METHOD FOR PRODUCING POLYURETHANE LENS Hoya Corporation (JP) 2014-07-09 EP claimed
US-4093780-A ESTERS AND POLYESTERS OF THIOGLYCOLIC ACID NORANDA MINES LIMITED (CA) 1978-06-06 US claimed
US-11267953-B2 Iso(thio)cyanate composition, and resin composition including same for optical member HOYA LENS THAILAND LTD. (TH) 2022-03-08 US disclosed
EP-3957666-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER Hoya Lens Thailand Ltd. (TH) 2022-02-23 EP disclosed
EP-3269749-B1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER HOYA LENS THAILAND LTD (TH) 2021-12-01 EP disclosed
US-20200123345-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER HOYA LENS THAILAND LTD. (TH) 2020-04-23 US disclosed
US-10544283-B2 Iso(thio)cyanate composition, and resin composition including same for optical member HOYA LENS THAILAND LTD. (TH) 2020-01-28 US disclosed
US-20180037722-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER HOYA LENS THAILAND LTD. (TH) 2018-02-08 US disclosed
EP-3269749-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER Hoya Lens Thailand Ltd. (TH) 2018-01-17 EP disclosed
EP-2752684-B1 METHOD FOR PRODUCING POLYURETHANE LENS HOYA CORP (JP) 2017-07-12 EP disclosed
US-20140296431-A1 METHOD FOR PRODUCING POLYURETHANE LENS HOYA CORPORATION (JP) 2014-10-02 US disclosed
EP-2752684-A1 METHOD FOR PRODUCING POLYURETHANE LENS Hoya Corporation (JP) 2014-07-09 EP disclosed
US-7399801-B2 Curable composition KANEKA CORPORATION (JP) 2008-07-15 US disclosed
US-20040249026-A1 Curable composition KANEKA CORPORATION (JP) 2004-12-09 US disclosed
EP-1447422-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-08-18 EP disclosed
US-4093780-A ESTERS AND POLYESTERS OF THIOGLYCOLIC ACID NORANDA MINES LIMITED (CA) 1978-06-06 US disclosed