SCHEMBL50780

SCHEMBL50780

CCOC1(O[Si](C)(C)C)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL15194619 0.98
SCHEMBL8532055 0.84 THRB (0.32)
SCHEMBL14361050 0.84
SCHEMBL4608050 0.78
SCHEMBL23293903 0.76
SCHEMBL4024768 0.73
SCHEMBL732380 0.73
SCHEMBL27860812 0.72
SCHEMBL6165114 0.70
SCHEMBL60218 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3304 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116803941-A Low-carbon high-strength corrosion-resistant tubular pile and preparation method thereof 江苏诚意工程技术研究院有限公司 2023-09-26 CN claimed
CN-113387799-B Preparation method of gamma, gamma-diaryl ester or gamma, gamma-triaryl ester compound and product thereof 南京工业大学 2021-12-21 CN claimed
CN-113387799-A Preparation method of gamma, gamma-diaryl ester or gamma, gamma-triaryl ester compound and product thereof 南京工业大学 2021-09-14 CN claimed
US-9093268-B2 Semiconductor device including porous low-k dielectric layer and fabrication method SEMICONDUCTOR MANUFACTURING INTERNATIONAL (SHANGHAI) CORPORATION (CN) 2015-07-28 US claimed
US-20140291817-A1 SEMICONDUCTOR DEVICE INCLUDING POROUS LOW-K DIELECTRIC LAYER AND FABRICATION METHOD SEMICONDUCTOR MANUFACTURING INTERNATIONAL (SHANGHAI) CORPORATION (CN) 2014-10-02 US claimed
EP-2246339-B1 Derivatives of benzothiazepine and their use as modulators of AMPA and NMDA receptors SERVIER LAB (FR) 2011-06-22 EP claimed
EP-1539739-B1 PIPERIDINYL COMPOUNDS THAT SELECTIVELY BIND INTEGRINS JANSSEN PHARMACEUTICA NV (BE) 2010-11-24 EP claimed
EP-2246339-A1 Derivatives of benzothiazepine and their use as modulators of AMPA and NMDA receptors Les Laboratoires Servier (FR) 2010-11-03 EP claimed
WO-2010106249-A1 BENZOTHIADIAZEPINE DERIVATIVES USED AS AMPA AND NMDA RECEPTOR MODULATORS LES LABORATOIRES SERVIER (FR) 2010-09-23 WO claimed
EP-2010488-A2 RENIN INHIBITORS Vitae Pharmaceuticals, Inc. (US) 2009-01-07 EP claimed
WO-2007117559-A2 RENIN INHIBITORS VITAE PHARMACEUTICALS, INC. (US) 2007-10-18 WO claimed
JP-11035530-A None JP disclosed
JP-10087584-A None JP disclosed
EP-4027995-B1 HPK1 ANTAGONISTS AND USES THEREOF NIMBUS SATURN INC (US) 2026-05-27 EP disclosed
WO-2026106912-A1 RAS INHIBITORS Revolution Medicines, Inc. (US) 2026-05-21 WO disclosed
EP-0557016-B1 Naphthalene derivatives, processes for preparing the same, and synthetic intermediates therefor TANABE SEIYAKU CO (JP) 1996-06-19 EP disclosed
WO-1995013262-A1 SUBSTITUTED PHENYL COMPOUNDS RHONE-POULENC RORER LIMITED (GB) 1995-05-18 WO disclosed
US-5342941-A Bronchodilating agents TANABE SEIYAKU CO., LTD. (JP) 1994-08-30 US disclosed
EP-0557016-A1 Naphthalene derivatives, processes for preparing the same, and synthetic intermediates therefor TANABE SEIYAKU CO., LTD. (JP) 1993-08-25 EP disclosed
US-4634705-A Adrenergic amidines ABBOTT LABORATORIES (US) 1987-01-06 US disclosed