Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 20/20 | 0.69 |
| ▸ | KCNJ11 | Q14654 | 20/20 | 0.69 |
| ▸ | ABCC8 | Q09428 | 10/20 | 0.69 |
| ▸ | KCNJ8 | Q15842 | 10/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5074902 | 0.92 | ABCC9 (0.56) | ABCC9KCNJ11ABCC8KCNJ8 | |
| SCHEMBL5072959 | 0.91 | ABCC9 (0.67) | ABCC9KCNJ11ABCC8KCNJ8 | |
| SCHEMBL5078105 | 0.88 | ABCC9 (0.63) | ABCC9KCNJ11ABCC8KCNJ8 | |
| Hydrochloric Acid SCHEMBL5079043 | 0.87 | ABCC9 (0.64) | ABCC9KCNJ11ABCC8KCNJ8 | |
| SCHEMBL5073076 | 0.83 | ABCC9 (1.00) | ABCC9KCNJ11ABCC8KCNJ8 | |
| SCHEMBL7943102 | 0.82 | ABCC9 (0.48) | ABCC9KCNJ11ABCC8KCNJ8 | |
| SCHEMBL5141498 | 0.81 | ABCC9 (0.66) | ABCC9KCNJ11ABCC8KCNJ8 | |
| SCHEMBL7943112 | 0.81 | ABCC9 (0.52) | ABCC9KCNJ11ABCC8KCNJ8 | |
| SCHEMBL5078962 | 0.80 | ABCC9 (0.67) | ABCC9KCNJ11ABCC8KCNJ8 | |
| SCHEMBL4261083 | 0.79 | ABCC9 (1.00) | ABCC9KCNJ11ABCC8KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124828-B1 | PYRANO, PIPERIDINO, AND THIOPYRANO COMPOUNDS AND METHODS OF USE | ABBOTT LAB (US) | 2008-01-02 | — | — | EP | disclosed |
| US-6191140-B1 | POTASSIUM CHANNEL MODULATORS; MUSCLE RELAXANTS; CONTROLLING CELL MEMBRANES | ABBOTT LABORATORIES | 2001-02-20 | — | — | US | disclosed |