SCHEMBL5078231

SCHEMBL5078231

Cc1c(CN(C)C(=O)C=Cc2cnc(N)c(CN3CCN(C)CC3)c2)sc2ccccc12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5078230 1.00
Hydrochloric Acid SCHEMBL1251715 0.99
Hydrochloric Acid SCHEMBL1251719 0.99
SCHEMBL5079762 0.91 KDM4E (0.38)
SCHEMBL5079756 0.91 KDM4E (0.38)
Hydrochloric Acid SCHEMBL1253910 0.91 KDM4E (0.39)
Hydrochloric Acid SCHEMBL1253912 0.91 KDM4E (0.39)
SCHEMBL5076267 0.84 KIT (0.41)
Hydrochloric Acid SCHEMBL1251765 0.83 KIT (0.40)
Hydrochloric Acid SCHEMBL1251761 0.83 KIT (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1608377-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS AFFINIUM PHARM INC (CA) 2008-10-01 EP claimed