Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5079762 | 1.00 | KDM4E (0.38) | KDM4EMAPTMAPK1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1253912 | 0.99 | KDM4E (0.39) | KDM4EMAPTMAPK1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1253910 | 0.99 | KDM4E (0.39) | KDM4EMAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL5078231 | 0.91 | — | — | |
| SCHEMBL5078230 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL1251715 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL1251719 | 0.91 | — | — | |
| SCHEMBL5079082 | 0.84 | SMN1; SMN2 (0.39) | KDM4EMAPTMAPK1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1254002 | 0.83 | SMN1; SMN2 (0.41) | KDM4EMAPTMAPK1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1253998 | 0.83 | SMN1; SMN2 (0.41) | KDM4EMAPTMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608377-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARM INC (CA) | 2008-10-01 | — | — | EP | claimed |