SCHEMBL5078657

SCHEMBL5078657

CCCC[Si](C)(C)OCC1(COCC)c2ccccc2-c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
PDK2 Q15119 3/20 0.32
MEN1 O00255 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5082307 0.93 CYP2C19 (0.36) CYP2C9CYP2C19NPSR1PDK2MEN1
SCHEMBL5082365 0.92 SMN1; SMN2 (0.31) CYP2C19KMT2ASMN1; SMN2
SCHEMBL5084634 0.91 CYP2C9 (0.34) CYP2C9CYP2C19NPSR1PDK2MEN1
SCHEMBL5082272 0.88 CYP2C9 (0.33) CYP2C9CYP2C19NPSR1PDK2MEN1
SCHEMBL5082314 0.86 SMN1; SMN2 (0.33) CYP2C19PDK2KMT2ASMN1; SMN2
SCHEMBL5085328 0.84 ALDH1A1 (0.33) L3MBTL1SMN1; SMN2
SCHEMBL5078725 0.84 APEX1 (0.34) CYP2C9CYP2C19NPSR1PDK2MEN1
SCHEMBL5078695 0.83 SMN1; SMN2 (0.34) CYP2C9CYP2C19PDK2KMT2ASMN1; SMN2
SCHEMBL5081723 0.82 PDK2 (0.33) CYP2C9CYP2C19NPSR1PDK2
SCHEMBL5085278 0.82 PDK2 (0.38) CYP2C9CYP2C19NPSR1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed