SCHEMBL5078798

SCHEMBL5078798

CCCc1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 9/20 0.57
ESR1 P03372 1/20 0.48
ALDH1A1 P00352 2/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
TTR P02766 1/20 0.44
CYP1A2 P05177 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
MAPK1 P28482 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27496251 0.90 GPR35 (0.46) GPR35ESR1ALDH1A1CRHBPCRHR2
SCHEMBL8736399 0.89 GPR35 (0.53) GPR35ESR1ALDH1A1CRHBPCRHR2
SCHEMBL7020103 0.88 GPR35 (0.44) GPR35ESR1ALDH1A1KDM4EMEN1
SCHEMBL1861075 0.86 ESR1 (0.57) GPR35ESR1
SCHEMBL8733612 0.86 ESR1 (0.57) GPR35ESR1
SCHEMBL11204852 0.86 ESR1 (0.57) GPR35ESR1
SCHEMBL11206702 0.86 ESR1 (0.57) GPR35ESR1
SCHEMBL11066481 0.85 GPR35 (0.42) GPR35ESR1ALDH1A1KDM4EMEN1
SCHEMBL5083291 0.84 GPR35 (0.61) GPR35ESR1ALDH1A1CRHBPCRHR2
SCHEMBL17867141 0.82 GPR35 (0.53) GPR35ALDH1A1CRHBPCRHR2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080200616-A1 Method of Inhibiting Polymerization Giving Copolymer of Divinylbenzene and Aromatic Vinyl Compound HAKUTO CO,. LTD. (JP) 2008-08-21 US disclosed
EP-1813585-A1 METHOD OF INHIBITING POLYMERIZATION GIVING COPOLYMER OF DIVINYLBENZENE AND AROMATIC VINYL COMPOUND Hakuto Co., Ltd (JP) 2007-08-01 EP disclosed