SCHEMBL5079197

SCHEMBL5079197

CP(C)c1ccccc1.CP(C)c1ccccc1.CP(C)c1ccccc1.N#CCCl.[W]

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTT P42858 1/20 0.31
LMNA P02545 1/20 0.31
MAOB P27338 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5076043 0.83 TDP1 (0.55) ESR1ESR2TDP1CYP3A4TSHR
SCHEMBL5115366 0.80 TDP1 (0.57) ESR1ESR2TDP1CYP3A4TSHR
SCHEMBL5074228 0.79 TDP1 (0.50) ESR1ESR2TDP1CYP3A4TSHR
SCHEMBL34204 0.76
SCHEMBL8052335 0.76
SCHEMBL5075526 0.74 CYP3A4 (0.45) ESR1ESR2TDP1CYP3A4TSHR
SCHEMBL19514044 0.74 CYP3A4 (0.45) ESR1ESR2TDP1CYP3A4TSHR
SCHEMBL11661411 0.74 CYP3A4 (0.45) ESR1ESR2TDP1CYP3A4TSHR
SCHEMBL23243497 0.74 TDP1 (0.50) ESR1ESR2TDP1CYP3A4TSHR
SCHEMBL9217677 0.74 TDP1 (0.50) ESR1ESR2TDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1205494-B1 Catalyst component and catalyst for addition polymerization, and process for producing addition polymers SUMITOMO CHEMICAL CO (JP) 2008-04-09 EP disclosed
US-6723807-B2 CYCLOPENTADIENE METAL COMPLEX WITH NITROGEN AND AN ORGANOALUMINUM, AND AN ALUMINOXANE AND/OR BORON COMPOUND; HIGH ACTIVITY. SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-20 US disclosed
US-20030158355-A1 Catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-21 US disclosed
US-20020091209-A1 Catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-07-11 US disclosed
EP-1205494-A1 Catalyst component and catalyst for addition polymerization, and process for producing addition polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020091209-A1 Catalyst component and catalyst for addition polymerization, and process for producing addition polymer ZYX, MLX, AP1M1 ESR1 4071/4885ESR2 3988/4885TDP1 4637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.