Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | BAX | Q07812 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648435 | 0.94 | LIG1 (0.46) | LIG1CTNNB1BCL2MCL1BAD | |
| SCHEMBL29514788 | 0.91 | CTNNB1 (0.53) | CTNNB1BCL2MCL1BADSRD5A2 | |
| SCHEMBL466195 | 0.91 | CTNNB1 (0.53) | CTNNB1BCL2MCL1BADSRD5A2 | |
| Benzophenone SCHEMBL28468677 | 0.88 | SRD5A2 (0.57) | CTNNB1BCL2MCL1BADSRD5A2 | |
| SCHEMBL9646984 | 0.85 | CTNNB1 (0.50) | CTNNB1BCL2MCL1BADSRD5A2 | |
| SCHEMBL10534226 | 0.83 | LIG1 (0.58) | LIG1CTNNB1BCL2MCL1BAD | |
| SCHEMBL10697260 | 0.81 | CTNNB1 (0.53) | LIG1CTNNB1SRD5A2LTA4HNR1H2 | |
| SCHEMBL29474396 | 0.81 | CTNNB1 (0.46) | CTNNB1SRD5A2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8974224 | 0.81 | CTNNB1 (0.46) | CTNNB1SRD5A2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8746846 | 0.81 | CTNNB1 (0.65) | CTNNB1BCL2MCL1BADSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359176-B1 | Polycarbonates, polyestercarbonates and polyesters having specific branched endgroups | BAYER MATERIALSCIENCE AG (DE) | 2008-08-27 | — | — | EP | disclosed |
| US-6825312-B2 | POLYCARBONATESTER COPOLYMER MOLDING MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-30 | — | — | US | disclosed |
| US-20040030090-A1 | Polycarbonates, polyester carbonates and polyesters with special branched terminal groups | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-12 | — | — | US | disclosed |
| EP-1359176-A2 | Polycarbonates, polyestercarbonates and polyesters having specific branched endgroups | Bayer Aktiengesellschaft (DE) | 2003-11-05 | — | — | EP | disclosed |