Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765874 | 0.82 | TOP2A (0.43) | TOP2ASLC22A12HDAC6HPGDNAPRT | |
| SCHEMBL27478753 | 0.82 | TOP2A (0.43) | TOP2ASLC22A12HDAC6HPGDNAPRT | |
| SCHEMBL27510144 | 0.80 | MEN1 (0.45) | TOP2ASLC22A12HDAC6HPGDNAPRT | |
| SCHEMBL28014454 | 0.76 | NPC1 (0.42) | HPGDNAPRTKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11163620 | 0.71 | NAPRT (0.34) | NAPRTHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL8414172 | 0.70 | POLB (0.53) | TOP2ASLC22A12HDAC6HPGDNAPRT | |
| SCHEMBL10339863 | 0.69 | HPGD (0.46) | TOP2ASLC22A12HDAC6HPGDNAPRT | |
| SCHEMBL11584096 | 0.69 | TSHR (0.38) | NAPRTHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL7172992 | 0.68 | POLA1 (0.33) | ALDH1A1 | |
| SCHEMBL28385912 | 0.68 | TOP2A (0.39) | TOP2ASLC22A12HDAC6HPGDNAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534657-B1 | PROCESS FOR PREPARING ALDEHYDE COMPOUNDS | INVISTA TECH SARL (CH) | 2008-10-08 | — | — | EP | disclosed |
| EP-1534657-A4 | PROCESS FOR PREPARING ALDEHYDE COMPOUNDS | INVISTA TECH SARL (US) | 2006-08-02 | — | — | EP | disclosed |
| EP-1534657-A1 | PROCESS FOR PREPARING ALDEHYDE COMPOUNDS | INVISTA Technologies S.à.r.l. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004020381-A1 | PROCESS FOR PREPARING ALDEHYDE COMPOUNDS | INVISTA TECHNOLOGIES S.À.R.L. (US) | 2004-03-11 | — | — | WO | disclosed |
| US-6664427-B1 | From an unsaturated compound by hydroformylation and in the presence of a catalyst system comprising a Group VIII metal and a bidentate phosphorus ligand having two trivalent phosphorus atoms bound to salicylanilide groups | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-12-16 | — | — | US | disclosed |