Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18772417 | 0.80 | TSHR (0.50) | TSHRCES1CES2SRCL3MBTL1 | |
| SCHEMBL4629606 | 0.78 | TSHR (0.48) | TSHRCES1CES2SRCL3MBTL1 | |
| SCHEMBL27691329 | 0.77 | TSHR (0.52) | TSHRCES1CES2SRCL3MBTL1 | |
| SCHEMBL20258664 | 0.76 | TSHR (0.42) | TSHRCES1CES2SRCLMNA | |
| SCHEMBL8975527 | 0.75 | TSHR (0.56) | TSHRCES1CES2SRCL3MBTL1 | |
| SCHEMBL817841 | 0.74 | TSHR (0.54) | TSHRCES1CES2SRCL3MBTL1 | |
| SCHEMBL28375112 | 0.73 | TSHR (0.54) | TSHRCES1CES2SRCL3MBTL1 | |
| SCHEMBL21561514 | 0.73 | TSHR (0.43) | TSHRCES1CES2SRCL3MBTL1 | |
| SCHEMBL18713396 | 0.73 | TSHR (0.54) | TSHRCES1CES2SRCLMNA | |
| SCHEMBL18884554 | 0.73 | CES2 (0.48) | TSHRCES1CES2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119250-A1 | INSECT REPELLENTS | QUEST INTERNATIONAL NEDERLAND BV (NL) | 2001-08-01 | — | — | EP | claimed |
| WO-2000019822-A1 | INSECT REPELLENTS | QUEST INTERNATIONAL B.V. (NL) | 2000-04-13 | — | — | WO | claimed |
| US-7455852-B2 | Insect repellents | QUEST INTERNATIONAL B.V. (NL) | 2008-11-25 | — | — | US | disclosed |
| EP-1414298-B1 | INSECT REPELLENTS | QUEST INT SERV BV (NL) | 2005-10-26 | — | — | EP | disclosed |
| US-20040213822-A1 | Insect repellents | QUEST INTERNATIONAL B.V. (NL) | 2004-10-28 | — | — | US | disclosed |