Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL451907 | 0.84 | CYP19A1 (0.32) | PDE5A | |
| Hydrochloric Acid SCHEMBL452344 | 0.80 | TSHR (0.31) | — | |
| Hydrochloric Acid SCHEMBL455226 | 0.80 | TSHR (0.31) | — | |
| Hydrochloric Acid SCHEMBL452987 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL450633 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL450582 | 0.79 | NPSR1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL453275 | 0.79 | PDE5A (0.33) | PDE5A | |
| Hydrochloric Acid SCHEMBL452682 | 0.79 | CNR2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL454870 | 0.78 | TSHR (0.31) | — | |
| Hydrochloric Acid SCHEMBL453773 | 0.78 | NPSR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964860-A1 | ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER | Tosoh Corporation (JP) | 2008-09-03 | — | — | EP | disclosed |