SCHEMBL5080322

SCHEMBL5080322

CNC(=O)/C(=N/OC)c1ccccc1COc1cc(Cl)c(Oc2ccc(C(F)(F)F)cn2)c(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.49
SCN9A Q15858 3/20 0.40
LMNA P02545 1/20 0.39
LIPE Q05469 4/20 0.39
MRGPRX4 Q96LA9 1/20 0.39
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SCN10A Q9Y5Y9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080327 1.00 HIF1A (0.49) HIF1ASCN9ALMNALIPEMRGPRX4
SCHEMBL5076415 0.92 HIF1A (0.59) HIF1ALMNALIPEMRGPRX4KMT2A
SCHEMBL6151255 0.91 HIF1A (0.49) HIF1ALMNALIPEMRGPRX4KMT2A
SCHEMBL6151253 0.91 HIF1A (0.49) HIF1ALMNALIPEMRGPRX4KMT2A
SCHEMBL5077016 0.89 HIF1A (0.52) HIF1AMRGPRX4
SCHEMBL5077022 0.89 HIF1A (0.52) HIF1AMRGPRX4
SCHEMBL8371691 0.86 HIF1A (0.51) HIF1ASCN9ALMNALIPEMRGPRX4
SCHEMBL8780155 0.86 HIF1A (0.51) HIF1ASCN9ALMNALIPEMRGPRX4
SCHEMBL8371689 0.86 HIF1A (0.51) HIF1ASCN9ALMNALIPEMRGPRX4
SCHEMBL5079438 0.84 HIF1A (0.51) HIF1ASCN9ALMNAMRGPRX4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT HIF1A 4554/4885SCN9A 1765/4885LMNA 4661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.