SCHEMBL6151253

SCHEMBL6151253

CO/N=C(/C(=O)O)c1ccccc1COc1cc(Cl)c(Oc2ccc(C(F)(F)F)cn2)c(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 6/20 0.49
LIPE Q05469 5/20 0.41
KMT2A Q03164 1/20 0.40
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.39
MRGPRX4 Q96LA9 3/20 0.39
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151255 1.00 HIF1A (0.49) HIF1ALIPEKMT2ATSHRSMN1; SMN2
SCHEMBL5076419 0.92 MAPK1 (0.41) HIF1ALIPEKMT2ATSHRSMN1; SMN2
SCHEMBL5076415 0.92 HIF1A (0.59) HIF1ALIPEKMT2ATSHRSMN1; SMN2
SCHEMBL5080322 0.91 HIF1A (0.49) HIF1ALIPEKMT2ATSHRSMN1; SMN2
SCHEMBL5080327 0.91 HIF1A (0.49) HIF1ALIPEKMT2ATSHRSMN1; SMN2
SCHEMBL6149076 0.89 HIF1A (0.52) HIF1AMRGPRX4
SCHEMBL6149075 0.89 HIF1A (0.52) HIF1AMRGPRX4
SCHEMBL5076451 0.85 LMNA (0.42) LIPEKMT2ATSHRSMN1; SMN2LMNA
SCHEMBL5076449 0.85 LIPE (0.42) LIPEKMT2ATSHRSMN1; SMN2LMNA
SCHEMBL6149567 0.85 LIPE (0.41) LIPEKMT2ATSHRSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed