Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | GRK2 | P25098 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080341 | 1.00 | L3MBTL1 (0.62) | L3MBTL1HTR1ACYP3A4TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL9397472 | 0.99 | L3MBTL1 (0.61) | L3MBTL1HTR1ACYP3A4TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL9398557 | 0.99 | L3MBTL1 (0.61) | L3MBTL1HTR1ACYP3A4TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL9397669 | 0.99 | L3MBTL1 (0.61) | L3MBTL1HTR1ACYP3A4TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL5079381 | 0.99 | L3MBTL1 (0.61) | L3MBTL1HTR1ACYP3A4TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL9397656 | 0.99 | L3MBTL1 (0.61) | L3MBTL1HTR1ACYP3A4TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL9397476 | 0.99 | L3MBTL1 (0.61) | L3MBTL1HTR1ACYP3A4TP53CYP1A2 | |
| SCHEMBL1151876 | 0.99 | L3MBTL1 (0.63) | L3MBTL1HTR1ACYP3A4TP53CYP1A2 | |
| SCHEMBL1151874 | 0.99 | L3MBTL1 (0.63) | L3MBTL1HTR1ACYP3A4TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL1152712 | 0.98 | L3MBTL1 (0.62) | L3MBTL1HTR1ACYP3A4TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133884-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-11-06 | — | — | WO | disclosed |