SCHEMBL5080348

SCHEMBL5080348

CCOCCOCCOc1c(Cl)cc(OCc2ccccc2/C(=C\OC)C(=O)OC)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.39
HIF1A Q16665 6/20 0.38
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MEN1 O00255 1/20 0.37
ABL1 P00519 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
RIN1 Q13671 1/20 0.37
KDM4E B2RXH2 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151408 0.91 TTR (0.39) TTRLMNASMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL6151410 0.91 TTR (0.39) TTRLMNASMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL5080526 0.90 ALDH1A1 (0.38) TTRLMNASMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL5080513 0.90 ALDH1A1 (0.38) TTRLMNASMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL6150595 0.86 HIF1A (0.40) HIF1ASMN1; SMN2L3MBTL1KDM4ETDP1
SCHEMBL5080423 0.85 HIF1A (0.39) HIF1A
SCHEMBL5075841 0.84 HIF1A (0.50) HIF1ALMNASMN1; SMN2ALDH1A1MEN1
SCHEMBL5074605 0.84 HIF1A (0.39) HIF1AMEN1MAPTRAB9AKMT2A
SCHEMBL5080519 0.83 ALDH1A1 (0.40) TTRLMNASMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL5076493 0.83 HIF1A (0.39) HIF1AALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT TTR 1910/4885HIF1A 4554/4885LMNA 4661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.