SCHEMBL5080387

SCHEMBL5080387

CCON=C(C(=O)O)c1ccccc1COc1cc(OCC2CC2(Cl)Cl)c(Cl)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 7/20 0.41
TP53 P04637 1/20 0.39
HTT P42858 1/20 0.39
PDCD1 Q15116 8/20 0.38
CD274 Q9NZQ7 8/20 0.38
HIF1A Q16665 2/20 0.34
S1PR1 P21453 1/20 0.34
S1PR5 Q9H228 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151025 0.92 HIF1A (0.43) MRGPRX4TP53HTTPDCD1CD274
SCHEMBL6151029 0.92 HIF1A (0.43) MRGPRX4TP53HTTPDCD1CD274
SCHEMBL5075864 0.88 PDCD1 (0.49) MRGPRX4TP53HTTPDCD1CD274
SCHEMBL5080538 0.87 MEN1 (0.36) MRGPRX4TP53HTTHIF1A
SCHEMBL5076413 0.87 HIF1A (0.38) MRGPRX4TP53HTTHIF1AS1PR1
SCHEMBL5080383 0.83 HIF1A (0.52) MRGPRX4TP53HTTPDCD1CD274
SCHEMBL6149439 0.83 MRGPRX4 (0.44) MRGPRX4TP53HTTPDCD1CD274
SCHEMBL5075838 0.83 MRGPRX4 (0.44) MRGPRX4TP53HTTPDCD1CD274
SCHEMBL5074506 0.82 HIF1A (0.42) MRGPRX4TP53HTTPDCD1CD274
SCHEMBL5074509 0.82 HIF1A (0.42) MRGPRX4TP53HTTPDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT MRGPRX4 989/4885TP53 2842/4885HTT 4420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.