SCHEMBL6151025

SCHEMBL6151025

CO/N=C(/C(=O)O)c1ccccc1COc1cc(OCC2CC2(Cl)Cl)c(Cl)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.43
MRGPRX4 Q96LA9 3/20 0.42
TP53 P04637 1/20 0.40
HTT P42858 1/20 0.40
PDCD1 Q15116 5/20 0.38
CD274 Q9NZQ7 5/20 0.38
S1PR1 P21453 1/20 0.36
S1PR5 Q9H228 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151029 1.00 HIF1A (0.43) HIF1AMRGPRX4TP53HTTPDCD1
SCHEMBL5080387 0.92 MRGPRX4 (0.41) HIF1AMRGPRX4TP53HTTPDCD1
SCHEMBL5080383 0.92 HIF1A (0.52) HIF1AMRGPRX4TP53HTTPDCD1
SCHEMBL5074509 0.90 HIF1A (0.42) HIF1AMRGPRX4TP53HTTPDCD1
SCHEMBL5074506 0.90 HIF1A (0.42) HIF1AMRGPRX4TP53HTTPDCD1
SCHEMBL6150443 0.87 PDCD1 (0.49) HIF1AMRGPRX4TP53HTTPDCD1
SCHEMBL6150439 0.87 PDCD1 (0.49) HIF1AMRGPRX4TP53HTTPDCD1
SCHEMBL6147843 0.87 HIF1A (0.45) HIF1AMRGPRX4TP53HTTS1PR1
SCHEMBL5079363 0.87 HIF1A (0.47) HIF1AMRGPRX4TP53HTTS1PR1
SCHEMBL5079371 0.87 HIF1A (0.47) HIF1AMRGPRX4TP53HTTS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed