Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8510029 | 0.91 | — | — | |
| SCHEMBL5550881 | 0.83 | TSHR (0.36) | TSHRTHRBALDH1A1TRPM8EPHX1 | |
| SCHEMBL28822985 | 0.83 | TSHR (0.36) | TSHRTHRBALDH1A1TRPM8EPHX1 | |
| SCHEMBL8509148 | 0.83 | TSHR (0.36) | TSHRTHRBALDH1A1TRPM8EPHX1 | |
| SCHEMBL8508109 | 0.81 | TSHR (0.35) | TSHRTHRBALDH1A1DNM1 | |
| SCHEMBL11313336 | 0.77 | TSHR (0.50) | TSHRTHRBALDH1A1EPHX1DNM1 | |
| SCHEMBL135669 | 0.77 | TSHR (0.50) | TSHRTHRBALDH1A1EPHX1DNM1 | |
| SCHEMBL8721998 | 0.77 | TSHR (0.30) | TSHR | |
| SCHEMBL134147 | 0.77 | TSHR (0.50) | TSHRTHRBALDH1A1EPHX1DNM1 | |
| SCHEMBL2763894 | 0.77 | TSHR (0.50) | TSHRTHRBALDH1A1EPHX1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381349-B2 | Process for producing liquid crystal of desired properties by mixing together at least two rigid rodlike helical polymers with narrow molecular weight distributions and different weight-average molecular weights with chiral side chains | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-06-03 | — | — | US | disclosed |
| US-20050224752-A1 | Process for producing liquid crystal of desired properties by mixing together at least two still rod-shaped polymers of narrow molecular weight distributions and different weight-average molecular weights having chiral side chain groups | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050224752-A1 | Process for producing liquid crystal of desired properties by mixing together at least two still rod-shaped polymers of narrow molecular weight distributions and different weight-average molecular weights having chiral side chain groups | RPL9; RPL9P7; RPL9P8; RPL9P9, CRYZ, RPL27 | TSHR 2882/4885THRB 3880/4885ALDH1A1 4694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.