Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | DUT | P33316 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080936 | 0.89 | PDK2 (0.32) | PDK2EHMT2CYP2C19 | |
| SCHEMBL5080883 | 0.89 | APEX1 (0.35) | PDK2EHMT2CYP2C9CYP2C19 | |
| SCHEMBL5084607 | 0.86 | PDK2 (0.35) | PDK2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL5081756 | 0.84 | PDK2 (0.34) | PDK2EHMT2CYP2C9 | |
| SCHEMBL20995933 | 0.84 | PDK2 (0.40) | PDK2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL30322467 | 0.84 | PDK2 (0.40) | PDK2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL5081777 | 0.83 | PDK2 (0.33) | PDK2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL5081723 | 0.82 | PDK2 (0.33) | PDK2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL5080886 | 0.82 | PDK2 (0.34) | PDK2CYP2C19 | |
| SCHEMBL5081819 | 0.81 | CYP2C9 (0.33) | PDK2CYP2C9CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142146-A1 | Catalyst for olefin polymerization and use of the same | CHINA PETROLEUM & CHEMICAL CORPORATION | 2006-06-29 | — | — | US | claimed |
| US-7323431-B2 | Catalyst for olefin polymerization and use of the same | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-01-29 | — | — | US | disclosed |
| US-20060142146-A1 | Catalyst for olefin polymerization and use of the same | CHINA PETROLEUM & CHEMICAL CORPORATION | 2006-06-29 | — | — | US | disclosed |
| US-6822109-B2 | TRIHYDROCARBYLSILYLATION; ADDITION POLYMERIZATION OF OLEFINS | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2004-11-23 | — | — | US | disclosed |
| US-20040106814-A1 | Silicon ether compound, a method for the preparation thereof and use thereof | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106814-A1 | Silicon ether compound, a method for the preparation thereof and use thereof | SIK1, CDK20, SGMS1 | PDK2 3730/4885EHMT2 4125/4885CYP2C9 920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.