Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HRH2 | P25021 | 3/20 | 0.55 |
| ▸ | HRH1 | P35367 | 3/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.54 |
| ▸ | STS | P08842 | 4/20 | 0.53 |
| ▸ | THRA | P10827 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL508105 | 1.00 | NPC1 (0.69) | NPC1L3MBTL1HRH2HRH1HSD17B3 | |
| SCHEMBL19043463 | 0.91 | NPC1 (0.83) | NPC1L3MBTL1HRH2HRH1HSD17B3 | |
| SCHEMBL11263173 | 0.90 | NPC1 (0.81) | NPC1L3MBTL1HRH2HRH1HSD17B3 | |
| SCHEMBL8404991 | 0.83 | KMT2A (0.50) | NPC1L3MBTL1 | |
| SCHEMBL11628115 | 0.83 | NPC1 (0.69) | NPC1L3MBTL1HRH2HRH1HSD17B3 | |
| SCHEMBL8404989 | 0.83 | KMT2A (0.50) | NPC1L3MBTL1 | |
| SCHEMBL28413264 | 0.82 | STS (0.53) | NPC1L3MBTL1HRH2HRH1HSD17B3 | |
| SCHEMBL28414791 | 0.82 | STS (0.53) | NPC1L3MBTL1HRH2HRH1HSD17B3 | |
| SCHEMBL18806573 | 0.82 | HSD17B3 (0.60) | NPC1L3MBTL1HSD17B3STSTHRA | |
| SCHEMBL11672253 | 0.82 | KMT2A (0.52) | NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435333-B2 | Photo-switchable membrane and method | UNIVERSITY OF ROCHESTER (US) | 2013-05-07 | — | — | US | disclosed |
| US-20120025136-A1 | PHOTO-SWITCHABLE MEMBRANE AND METHOD | UNIVERSITY OF ROCHESTER (US) | 2012-02-02 | — | — | US | disclosed |