Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.65 |
| ▸ | STS | P08842 | 4/20 | 0.64 |
| ▸ | THRA | P10827 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | HRH2 | P25021 | 4/20 | 0.62 |
| ▸ | HRH1 | P35367 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19043463 | 0.98 | NPC1 (0.83) | NPC1L3MBTL1HSD17B3STSTHRA | |
| SCHEMBL508105 | 0.90 | NPC1 (0.69) | NPC1L3MBTL1HSD17B3STSTHRA | |
| SCHEMBL11628115 | 0.90 | NPC1 (0.69) | NPC1L3MBTL1HSD17B3STSHRH2 | |
| SCHEMBL508104 | 0.90 | NPC1 (0.69) | NPC1L3MBTL1HSD17B3STSTHRA | |
| SCHEMBL20382633 | 0.89 | NPC1 (0.78) | NPC1L3MBTL1HSD17B3STS | |
| SCHEMBL29052113 | 0.89 | L3MBTL1 (0.64) | NPC1L3MBTL1HSD17B3STSTHRA | |
| SCHEMBL7923674 | 0.87 | NPC1 (0.81) | NPC1L3MBTL1STS | |
| SCHEMBL11440823 | 0.87 | L3MBTL1 (0.76) | NPC1L3MBTL1THRATHRBHRH2 | |
| SCHEMBL11349120 | 0.86 | HSD17B3 (0.69) | NPC1L3MBTL1HSD17B3STSTHRA | |
| SCHEMBL15199293 | 0.86 | L3MBTL1 (0.60) | NPC1L3MBTL1HSD17B3STSTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362450-A | Torque stabilizing method for fasteners and torque stabilized fasteners | NIPPON OIL AND FATS CO. LTD. (JP) | 1982-12-07 | — | — | US | disclosed |