Phthalic Acid

Phthalic Acid

SCHEMBL5081349

CC(C)CCC(CO)(CO)C(C)C.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
ALOX15 P16050 1/20 0.44
KDM4E B2RXH2 3/20 0.43
HSD17B10 Q99714 1/20 0.43
MYC P01106 3/20 0.39
NR4A1 P22736 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
HMGB1 P09429 1/20 0.39
HPGD P15428 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA7 P43166 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CA9 Q16790 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
CA14 Q9ULX7 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5079332 0.93 LTB4R2 (0.43) ALDH1A1KDM4EHSD17B10MYCLTB4R2
Benzoic Acid SCHEMBL561535 0.88 MAPK1 (0.46) KDM4EHSD17B10SMN1; SMN2NAPRTMAPT
Benzoic Acid SCHEMBL4577223 0.88 MAPK1 (0.46) KDM4EHSD17B10SMN1; SMN2NAPRTMAPT
SCHEMBL4839324 0.87 ALDH1A1 (0.46) ALDH1A1ALOX15KDM4EHSD17B10CA2
Benzoic Acid SCHEMBL29006857 0.81 MAPK1 (0.41) KDM4EHSD17B10SMN1; SMN2NAPRTMAPT
Benzoyl Formic Acid SCHEMBL16045154 0.81 MAPK1 (0.41) ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2
SCHEMBL5079328 0.81 ALDH1A1 (0.40) ALDH1A1KDM4EHSD17B10MAPTLTB4R2
Benzoic Acid SCHEMBL28694509 0.80 MAPK1 (0.44) NR4A1SMN1; SMN2NAPRTHTTTSHR
SCHEMBL5081347 0.80 TSHR (0.50) ALDH1A1CA2TDP1HTTTP53
Benzoic Acid SCHEMBL29006820 0.79 MAPK1 (0.40) ALDH1A1SMN1; SMN2NAPRTMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP claimed
EP-1666505-B1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2016-03-23 EP disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed